Manataka® American Indian Council







Native Remedies   


Natural herbal

antioxidant supplement

to support the common aging process.


Bio-Oxidate Defense

Supports cell integrity with natural antioxidants to discourage aging due to lifestyle factors

Bio-Oxidate Defense Benefits:

  • Acts as a natural antioxidant to promote cell health

  • Supports the cell integrity of each cell in the body

  • Discourages common aging due to lifestyle factors

  • Encourages the body’s ability to counteract the effects of oxidization on cells

  • Encourages overall systemic health and support of the immune system

Related Products:

  • To promote routine balance in the body across all body systems visit AdaptoZen™


"...I feel ten years younger. It’s one thing to eat right and exercise, but at least now I know I am also doing something from the inside out. Thanks for a great product and keep them coming..." - Edward


Better Building Blocks for Better Structure

In essence, the body is the sum of all our cells, with the human cell acting as the smallest building block. Cells make up tissues and tissues make up our organs. Organs then work together to make up body systems. Therefore, for health to flourish, cell integrity is essential. Strong cells mean strong, sound health. However, there are unseen, unavoidable ‘enemies’ of cells, called oxidants or free radicals.

What are Free Radicals?

A free radical or oxidant is produced when cells in the body burn oxygen to produce energy. They are also caused internally by normal metabolism.

Free radicals are unstable because they have one or more unpaired electrons. This electron inequality causes the free radicals to attack other cells, grabbing electrons of good cells, and thereby damaging good cells.

Cellular degeneration is a common pathway for aging. The free-radical theory of aging is that organisms age because cells accumulate free radical damage with the passage of time. Just as cars rust due to oxygen exposure to iron, cells age from the oxidation damage.

Environmental factors such as pollution, sunlight, x-rays, smoking and alcohol consumption also contribute to the formation of free radicals. Furthermore, modern Western diets, the use of recreational drugs and prescription medicines also take their toll on health at a cellular level. The body relies on every organ to function properly as they should. Cell integrity is vital for this process. When one body system is compromised, a domino effect is created, with one system affecting the next.

As the years go by and oxidation of cells increases, external and internal symptoms of aging appear. Most of us associate aging with sagging skin, wrinkles and gray hair. While these symptoms may be the most aesthetically annoying, a similar process is occurring inside the body and affecting all body systems, leading to a variety of health problems.

Antioxidants can help counteract the damage of good cells in the body caused by oxidation, neutralizing free radicals and help to prevent cell damage and therefore slow the symptoms of aging.

The Natural Way

Antioxidants can be found in many foods, especially vegetables and fruits. Vitamin E, Vitamin C, Vitamin A, and beta carotene are all good sources of antioxidants. These can be found in a balanced diet including walnuts, peanuts, almonds, olives avocados, fish oils, whole grains, apricots, citrus fruits, green veggies and milk.

Natural remedies have been used in traditional medicine for thousands of years to support the body’s ability to promote health on a cellular level and to prevent cell damage. Research has confirmed this traditional wisdom, and there are now many published clinical studies demonstrating the ability of a range of herbs to have antioxidant properties. (e.g. Standley L, Winterton P, Marnewick JL, et al. “Influence of processing stages on antimutagenic and antioxidant potentials of rooibos tea”. J Agric Food Chem 2001;49:114–7).

What is Bio-Oxidate Defense?

Bio-Oxidate Defense is a 100% safe, non-addictive natural herbal remedy formulated by a team of experts in the field of natural medicine. Bio-Oxidate Defense can be used consistently to safely support cell integrity.

Bio-Oxidate Defense contains a selection of herbs high in antioxidant properties that are well-known for their supportive function in maintaining healthy cellular processes.

Bio-Oxidate Defense supports the body’s ability to fight harmful free radicals, thereby helping to maintain routine performance of bodily systems and encourage a slower hand of time.

The formula remains true to the whole spectrum method of herbal extraction, ensuring the bio-availability and balance of all the active ingredients contained in the remedy. This method of manufacture also significantly reduces the likelihood of side effects and maintains all active ingredients in perfect balance – exactly as nature intended! 

All Native Remedies homeopathic products and biochemic tissue salts are manufactured in an FDA and GMP registered pharmaceutical facility under the supervision of qualified homeopaths and responsible pharmacists. Individual ingredients are listed in the Homeopathic Pharmacopoeia of the United States (HPUS).


How has Bio-Oxidate Defense helped others?

I’ve bought every lotion out there to look younger and feel more youthful. Every cream on the market today seems to claim antioxidant properties. But this product help cells in my body at the root of it all! Just brilliant!!!—Dorothy, IL, USA

Hi. I have tried to lead a healthy lifestyle, but with all the pollution in the world, it sometimes feels pointless. Thank you for a product that helps to support my body against all that life throws at it! ”  — Linus

I had to write in and tell you my story. I will be 63 this December. A while ago I entered our town’s beauty pageant under the ‘grandmother and granddaughter’ division. After using your product, when I entered this year, the lady at the desk thought I was in the wrong division!! She couldn’t believe how wonderful I looked for my age. I think I have you to thank! So THANK YOU!”  —Shelly-Anne, KY, USA


Disclaimer: Testimonials have been edited to comply with FDA regulations. While positive results are likely, the testimonials used are general results and are not intended to represent or guarantee that anyone will achieve the same or similar results - individual results may vary.



What are the Ingredients?

Bio-Oxidate Defense is a 100% herbal formula containing carefully selected herbs in therapeutic dosage, presented in a 100% vege capsule:

Native Remedies' products are created using our Full Spectrum Approach™ (FSA), a set of standards and processes that combine the best quality, laboratory tested, raw ingredients, Good Manufacturing Practices and a Full Spectrum manufacturing method to guarantee you products of the highest quality, safety and effectiveness, all backed by our One Year Unconditional Money Back Guarantee.

Our products are not tested on animals and individual ingredients are well-researched and are natural, safe and effective.

  • Rooibos (Aspalathus linearis) is an herb found only on the slopes of the Cedarberg mountains in the Western Cape of South Africa, and has been used as a natural medicine for thousands of years by the indigenous people of that area. It is used as a supportive tonic and has powerful antioxidant properties, mainly due to its superoxide dismutase (SOD) mimetic properties. SOD is an enzyme in the body that is especially designed to neutralize unstable oxygen molecules (free radicals) as soon as they occur, and systemic SOD can therefore help to promote health. (Standley L, Winterton P, Marnewick JL, et al. “Influence of processing stages on antimutagenic and antioxidant potentials of rooibos tea”. J Agric Food Chem 2001;49:114–7). Due to its high vitamin and mineral content, Rooibos can promote healthy cell metabolism. These minerals can also be beneficial as a promotional tonic for the immune system. Rooibos is an extremely nutritious herb, containing Vitamin C, Alphahydroxy Acid, potassium, copper, magnesium, calcium, iron, zinc, manganese and fluoride. (Nakano M, Itoh Y, Mizuno T, Nakashima H. “Polysaccharide from Aspalathus linearis with strong anti-HIV activity”. Biosci Biotechnol Biochem 1997;61:267–71). (Nakano M, Nakashima H, Itoh Y. “Anti-human immunodeficiency virus activity of oligosaccharides from rooibos tea (Aspalathus linearis) extracts in vitro”. Leukemia 1997;11(Suppl. 3):128–30.)

  • Grape seed extract (vitis vinifera) is a potent source of proanthocyanidins and of pycnogenols a naturally powerful antioxidant. The way in which these versatile compounds are distinct from flavonoids is their simple chemical structure, which allows them to be readily absorbed into the bloodstream. OPC’s are also active against both fat and water-soluble oxidants. (Simonetti P, Ciappellano S, Gardana C, Bramati L, Pietta P. “Procyanidins from Vitis vinifera seeds: in vivo effects on oxidative stress”. J Agric Food Chem. 2002 Oct 9;50(21):6217-21). Grape seed extract has also been studied for its promotion of skin cell renewal. (Agarwal C, Singh RP, Dhanalakshmi S, Agarwal R. “Anti-angiogenic efficacy of grape seed extract in endothelial cells”. Oncol Rep. 2004 Mar;11(3):681-5). Grape seed extract has also been investigated for its affect on free radicals and thus its promotion of health. (Bagchi D, Bagchi M, Stohs SJ, Das DK, Ray SD, Kuszynski CA, Joshi SS, Pruess HG. “Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention”. Toxicology. 2000 Aug 7;148(2-3):187-97.)

  • Green tea (Camellia sinensis) is the tea plant, the plant species whose leaves and leaf buds are used to produce tea. White tea, green tea, oolong and black tea are all harvested from this species, but are processed differently to attain different levels of oxidation. Green tea contains high levels of substances called catechin polyphenols, known to possess strong antioxidant, anticarcinogenic, antitumorigenic, and even antibiotic properties. (Snow JM. Camellia sinensi (L.) Kuntze (Theaceae). J Botanical Medicine. 1995; Autumn:28-32). Green tea has also been investigated for its positive effect on aging skin. (Chiu AE, Chan JL, Kern DG, et al. “Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin”. Dermatol Surg. 2005;31:855-860; discussion 860). Green tea extract has also been studied in recent times for its ability to help address lipid imbalances in the blood. (Maron DJ, Lu GP, Cai NS, et al. “Cholesterol-lowering effect of a theaflavin-enriched green tea extract: a randomized controlled trial”. Arch Intern Med. 2003;163:1448-53.)

How do I use Bio-Oxidate Defense? 

DIRECTIONS: Take two capsules three times daily. Use regularly for best effect.

CAUTION: Safety during pregnancy and breastfeeding has not been established.

Bio-Oxidate Defense is highly recommended along with the following natural remedies for maximum effectiveness.

  • AdaptoZen is used to promote routine balance in the body across all body systems

  • VitaliTonic is used to provide herbal support for people over fifty

  • MemoRise is used for mature minds to support cognitive tasks and promote brain health

How long until I see results?

Results may vary, due to a number of influential factors. Many individuals experience systemic support within the first week. However, over time (usually 3-6 weeks) Bio-Oxidate Defense will act in a supportive capacity to cellular health and harmony. Some individuals respond sooner than others.

Get optimum results with regular use

While conventional medicine works by often treating just the symptoms, natural medicine strives to create holistic balance in the body to support systemic health, relieve ailments, and help prevent future disease. Unlike pharmaceutical drugs, the natural ingredients in our remedies support overall health and functioning (rather than just suppressing symptoms).  

People respond to natural medicine in different ways, some of our satisfied customers experience immediate results while many others have reported optimal benefits taking effect within 3-6 weeks. To ensure you receive optimum results it is important to take natural remedies as directed and remain consistent. You may also find that a smaller maintenance dose is beneficial for ongoing support, many customers report taking a regular maintenance dose as part of a preventative program for continued health and well-being.

How long will a bottle last?

One bottle of Bio-Oxidate Defense will last 10 days at full adult dosage (2 capsules three times daily)


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Bio-Oxidate Defense

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Retail Price: $54.95

Your Price: $43.95

Shipping & Handling
USA: $5.99 for the first item, $1 additional per extra item.
Canada: $13.99 for the first item, $1 additional per item
Worldwide: $15.99 for the first item, $1 additional per item.

ComboPacks consist of multiple remedies that work well together to provide increased support at a discounted price. One of each described.


Bio-Oxidate Defense

+ AdaptoZen

+ VitaliTonic

(1 ea) $115.95 + S&H

Promote systemic balance, health and vitality with added anti-oxidant defense (one of each)  

Bio-Oxidate Defense

+ AdaptoZen

+ VitaliTonic

+ Joint Ease Plus

(1 ea.) $139.95 + S&H  

Promote systemic balance, health and vitality and support joint health with added anti-oxidant defense (one of each)  

Bio-Oxidate Defense

+ AdaptoZen

+ VitaliTonic

+ Ikawe for Men

(1 ea.) $139.95 + S&H  


The Power Pack for Men

Promote systemic health, balance and vitality with added male sexual health tonic. AdaptoZen, VitaliTonic, Bio-Oxidate and Ikawe for Men (one of ea)


Bio-Oxidate Defense

+ AdaptoZen

+ VitaliTonic

+ Thanda Passion Booster

(1 ea.) $139.95 + S&H  


The Power Pack for Women

Promote systemic health, balance and vitality with added female sexual health tonic. AdaptoZen, VitaliTonic, Bio-Oxidate and Thanda Passion Booster (one of each)


* These statements have not been evaluated by the Food and Drug Administration. 

This product is not intended to diagnose, treat, cure or prevent any disease.


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